The name ‘ diabetes ‘ is derived from the Greek word for ' syphen '.

It is a disease of great antiquity, and some of it’s salient features have been
known since the second century AD when Aretaeus described it as ' a melting of
the flesh and limbs into the urine '.

Thomas willis (of the circle fame ) noted that the urine was ' wonderfully sweet
as if it were imbued with honey or sugar '. Hence the term ' mellitus ', derived
from the Latin word for honey.

When Banting and best isolated insulin from the pancreas, the almost miraculous
effect of injecting it into patients with severe diabetes was heralded as a cure
for the disease. However, it became apparent that many diabetic subjects
require injections of insulin in quantities far in excess of those required by a
totally pancreatectomised individual.

Factors other than insulin deficiency are involved and indeed the blood insulin
level in some patients is normal or even in excess of normal.

Finally, it is now apparent that while insulin therapy can prolong the life of
some diabetic subjects, it fails to prevent premature death from the
cardiovascular complications, particularly coronary artery disease, or the onset
of blindness.
Diabetes Mellitus
Diabetes Dictionary   Pancreatic Physiology   Types of Diabetes   Pathogenesis   Incidence    

Etiology   Pathophysiology   Clinical Evaluation    Complications   Risk Factors   Life style and nutrition    

Exercise   Insulin Therapy    Molecular mechanism of insulin    Oral Hypoglycemics  References
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